miRNA-Transcriptomic Open Project (miRTOP)

Citation: 10.5281/zenodo.45385

Project Status: WIP - Initial development is in progress, but there has not yet been a stable, usable release suitable for the public.


The main goal of this project is to create a reflection group on metazoan miRNAs, open to all interested researchers, to identify blockages and develop standards and guidelines to improve miRNA research, resources and communication. This can go through the use of standardized file formats, gene and variants nomenclature guidelines, and advancements in miRNA biology understanding. The group will eventually also aim at expanding its breadth to the development of novel tools, data resources, and best-practices guidelines to benefit the scientific community by providing high confidence validated research and analysis strategies, regardless the expertise in this field.

Read Road trip 2017


The motivation and emergence of this group came from the simultaneous publication of two articles from two independent groups and addressing the question of miRNA diversity, origins, evolution, and annotation:

In addition, plants miRNA research is facing the same problems. The different origin of plant and metazoan miRNA systems, however, make the creation of a unified “plant & metazoan” pattern hazardous. Nevertheless, tentative standardization on specific aspects is a future goal of the group.


If you work in relation with the miRNA field, and want to take part in this reflection group, please join us and share your ideas in order to create a large community working together to improve the study and analysis of miRNA data.

The idea is to add knowledge here, where people have easily access to the most used tools, or the best way to create/use data, or what are the current challenges we face nowadays. This project won't lead to publication by itself, but it will bring together researchers working in this field, that of course can lead to collaboration, that could result in publications to be added here. The way the content will be added is by proposing a topic/paper/tool in the github issue tracker page, after discussion collaborators will decide the following steps for the proposal.

Current projects:

Future projects and discussions: